The Gallaghers adjust to life during the pandemic: Frank fears the loss of the South Side to gentrification, while bar closures force Kev and V to get creative at the Alibi. Sleep-deprived Lip and Tami work to make their new house a home as Carl finishes his time at the police academy. Debbie becomes her own boss and deals with the repercussions of her statutory rape conviction of 17-year-old Julia. Ian and Mickey's honeymoon phase is over as they have very different ideas about what married life would be.
- William H. Macy - Frank Gallagher
- Jeremy Allen White - Phillip Gallagher
- Cameron Monaghan - Ian Gallagher
- Ethan Cutkosky - Carl Gallagher
- Shanola Hampton- Veronica Fisher
- Steve Howey - Kevin Ball
- Emma Kenney - Debbie Gallagher
- Noel Fisher - Mickey Milkovich
- Christian Isaiah - Liam Gallagher
- Kate Miner - Tami Tamietti
- This episode deals with the recent pandemic of COVID-19.
- Six months have passed since season 10.
- Lip and Tami are nearly done with their renovations.
- Lip has gotten his job at the motorcycle shop back
- Tami reveals she had COVID before.
- Debbie is placed on probation for statutory rape and wears an ankle bracelet.
- Julia testified against Debbie in court about their fling.
- Debbie is also required to register as a sex offender. Due to this, many residents are now worried to be around her and her attempts to find a job are slim.
- Carl was not charged with statutory rape, most likely because Claudia never knew of him and Julia being together.
- Julia is revealed to be ten months younger than Debbie.
- It is implied that Julia has return to living with her mother, due to the fact that she is not present at the Gallagher house.
- Sandy is still seeing Debbie.
- Mickey and Ian are saving up money.
- Carl is now training to be a police officer.
- Carl testifies against Odell and his garbage crew.
- Carl is said to be 19 years old.
- Freddie is said to be teething.
- Frank has no interaction with his kids in the season premiere.
- Kev shaves his head, as he was balding.
- Kevin reveals his twin girls are five years old.